Exposure to tri-o-cresyl phosphate detected in jet airplane passengers

Disturbed phospholipid homeostasis in endoplasmic reticulum initiates tri-o-cresyl phosphate-induced delayed neurotoxicity

Tri-o-cresyl phosphate (TOCP) is a widely used organophosphorus compound, which can cause a neurodegenerative disorder, i.e., organophosphate-induced delayed neurotoxicity (OPIDN). The biochemical events in the initiation of OPIDN were not fully understood except for the essential inhibition of neuropathy target esterase (NTE). NTE, located in endoplasmic reticulum (ER), catalyzes the deacylati...

Interim Specific Ground Water Criterion - Tri-ortho-cresyl phosphate (TOCP)

[A case of tri-ortho-cresyl-phosphate poisoning].

An outbreak of tri-ortho-cresyl phosphate (T.O.C.P.) poisoning in Durban.

Tri-ortho-cresyl phosphate (T.O.C.P.) is an organic phosphorus compound commonly used in industry as a plasticizer, and is so used in the manufacture of lacquers, dopes, synthetic fabrics, and synthetic lignin resin; it is used as a water-proofing agent in textile manufacture. It is said to be an excellent grinding medium for pigments; it is also used in making polyvinyl chloride sheeting and f...

Clinical Observation of Acute Delayed Neurotoxicity of Tri Ortho Cresyl Phosphate in Adult Hen

Clinical observation of acute delayed neurotoxicity study for 21 days of organophosphate using triorthocresyl phosphate (TOCP) as a model for organophosphate neurotoxicity, adult hens were dosed by oral gavage with 500mg/kg/bw single dose. Treated hens showed varying degrees of in-coordination, ataxia and paralysis at varying grades and on varying days of treatment mostly depending on the vario...